Work is central to people’s well-being. Due to the importance of work in improving the lives of persons with disability and its role in obtaining their rights to economic participation, achieving their independence, equal opportunities, and improving their lives and those of their families, which leads to their active contribution to economic growth. The study aimed to shed light on the economic participation of persons with mobility disability, specifically in the labour market in Kasbat Irbid, and to identify the challenges that prevent their effective economic participation.